2',3'-双脱氧腺苷 CAS#: 4097-22-7

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2',3'-双脱氧腺苷

生物活性靶点体外研究 用途与合成方法 MSDS 2',3'-双脱氧腺苷价格(试剂级) 上下游产品信息

中文名称	2',3'-双脱氧腺苷
中文同义词	2',3'-二脱氧腺苷(DDA);3'-双脱氧腺苷;2',3'-双脱氧腺甙;2',3'-双脱氧腺苷;2',3'-二脱氧腺苷2,3-二脱氧腺苷二脱氧腺(嘌呤核)苷2',3'-双脱氧腺苷2',3'-双脱氧腺甙双脱氧腺嘌呤核苷;去羟肌苷杂质B;双脱氧腺苷;2',3'-双脱氧腺苷(DDA)
英文名称	Dideoxyadenosine
英文同义词	[(2S,5R)-5-(6-Aminopurin-9-yl)oxolan-2-yl]methanol;NSC 98700;Didanosine Related CoMpound B;2',3'-DIDEOXYADENOSINE extapure;2’,3’-dideoxy-adenosin;2',3'-Dideoxy-D-adenosine;9-(2,3-Dideoxy-beta-D-ribofuranosyl)adenine;Didanosine Impurity 7（Didanosine EP Impurity G）
CAS号	4097-22-7
分子式	C10H13N5O2
分子量	235.24
EINECS号	223-853-2
相关类别	核苷，核苷酸，寡核苷酸;化学试剂;双脱氧核苷;其他生化试剂;生化试剂;修饰核苷;医药原料;脱氧核苷;Carbohydrates & Derivatives;Heterocycles;Intermediates & Fine Chemicals;Nucleotides;Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Bases & Related Reagents;Pharmaceuticals;Isotope Labelled Compounds
Mol文件	4097-22-7.mol
结构式

2',3'-双脱氧腺苷 性质

2',3'-双脱氧腺苷 用途与合成方法

生物活性

2',3'-Dideoxyadenosine 是 HIV 复制抑制剂。抗逆转录病毒活性。抗病毒活性 [1]。

靶点

HIV

体外研究

2',3'-Dideoxyadenosine inhibits HIV-1 and simian immunodeficiency virus (SIV) in MT-4 cells with EC     ₅₀    s of 5.27 and 5.3 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in human T-lymphocyte CEM cells with EC     ₅₀    s of 4 μM and 8 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in Molt 4/C8 cells with EC     ₅₀    s of 4 μM and 5.5 μM, respectively. 2',3'-Dideoxyadenosine inhibits HIV-1 and HIV-2 in C8166 cells with EC     ₅₀    s of 17 μM and 22 μM, respectively. 2',3'-Dideoxyadenosine inhibits murine sarcoma virus (MSV) in C3H/3T3 cells with an EC     ₅₀    of 24 μM.

用途 

用作抗病毒药

安全信息

MSDS信息

2',3'-双脱氧腺苷 价格(试剂级)

2',3'-双脱氧腺苷 上下游产品信息