兰色染料 CAS#: 12236-82-7

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兰色染料

生物活性体外研究 用途与合成方法 MSDS 兰色染料价格(试剂级) 上下游产品信息

中文名称	兰色染料
中文同义词	汽巴蓝 3GA 琼脂糖;蓝色染料;汽巴蓝/兰色染料;汽巴蓝F3GA;C.I.活性蓝2;兰色染料;活性蓝2;化合物 T19049
英文名称	REACTIVE BLUE 2
英文同义词	REACTIVE BLUE 2 C.I. NO. 61211;Procion Blue HB, pure;2-Anthracenesulfonic acid, 1-amino-4-4-4-chloro-6-3(or 4)-sulfophenylamino-1,3,5-triazin-2-ylamino-3-sulfophenylamino-9,10-dihydro-9,10-dioxo-;C.I.REACTIVEBLUE2;CIBRACONBLUEF3GA;Reactive blue 2 (C.I. 61211);Kayacion Blue A-B;1-Amino-4-[[4-[[4-chloro-6-[[4-(sodiooxysulfonyl)phenyl]amino]-1,3,5-triazin-2-yl]amino]-3-(sodiooxysulfonyl)phenyl]amino]-9,10-dihydro-9,10-dioxo-2-anthracenesulfonic acid sodium salt
CAS号	12236-82-7
分子式	C29H20ClN7O11S3
分子量	774.16
EINECS号	235-465-0
相关类别	Affinity  Chromatography;Dye  Resins;Protein  Chromatography;C;Stains  and  Dyes;Stains&Dyes,  A  to
Mol文件	12236-82-7.mol
结构式

兰色染料 性质

兰色染料 用途与合成方法

生物活性

Procion Blue HB (Reactive Blue 2)是嘌呤能拮抗剂。

体外研究

Reactive Blue 2 is used as an ATP receptor antagonist and induces Ca     ²⁺    oscillations in HeLa cells. Reactive Blue 2 enhances a Ca     ²⁺    response to histamine that is linked to the PLC cascade. Reactive Blue 2 may activate the PLC cascade in an extracellular Ca     ²⁺    -dependent manner and induce Ca     ²⁺    oscillations. The application of Reactive Blue 2 increases K     ⁺    secretion in a dose-dependent manner, and this increase is characterized as a peak followed by a partial relaxation to a steady-state. Reactive Blue 2 has antagonistic activities at P2Y4, and the antagonist potency at P2Y4 paralleled the potency of K+ secretion.The anthraquinone dye reactive blue 2 is found to be a potent inhibitor of a protein kinase isolated and purified from thylakoids. The mode of inhibition is noncompetitive, with a K     _i    of 8 μM for the membrane-bound kinase, and 6 microM for the purified kinase. The inhibitor does not modify the substrate preference of the endogenous kinase and could be removed from the membrane by washing. Reactive blue 2 selectively inhibits responses mediated via the P2ypurinoceptor, at least within a limited concentration range. In preparations where the tone has been raised with noradrenaline, ATP and 2-methylthio ATP, but not α,β-methylene ATP, produce relaxations of the vessel. These relaxations are inhibited in the presence of reactive blue 2. Reactive blue 2, at concentrations of 0.3-10 μM blocks the ATP-induced oscillation in a concentration-dependent manner.

安全信息

MSDS信息

兰色染料 价格(试剂级)

兰色染料 上下游产品信息

上游原料

2,5-二氨基苯磺酸对氨基苯磺酸3-氨基苯磺酸溴氨酸三聚氯氰