8-OH-脱氧鸟嘌呤 CAS#: 88847-89-6

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8-OH-脱氧鸟嘌呤

生物活性靶点体外研究 用途与合成方法 MSDS 8-OH-脱氧鸟嘌呤价格(试剂级) 上下游产品信息

中文名称	8-OH-脱氧鸟嘌呤
中文同义词	8-OH-脱氧鸟嘌呤;8-羟基-2'-脱氧鸟嘌呤;2'-脱氧-7,8-二氢-8-氧代鸟苷;8-羟基-2-脱氧鸟苷;8-羟基脱氧鸟苷;2'-脱氧-8-氧代鸟嘌呤;8-氧-2'-脱氧鸟苷;核酸氧化8-羟基脱氧鸟苷
英文名称	8-OXO-2'-DEOXYGUANOSINE
英文同义词	8-HYDROXY-2'-DEOXYGUANOSINE;2'-Deoxy-8-oxoguanosine;7,8-Dihydro-8-oxo-2'-deoxyguanosine;8-Oxo-7,8-dihydro-2'-deoxyguanosine;8-Oxo-7,8-dihydrodeoxyguanosine;2'-Deoxy-8-oxo-D-guanosine;8-Oxo-7,8-dihydro-2μ-deoxyguanosine,  8-Oxo-dG;2'-Deoxy-8-hydroxyguanosine
CAS号	88847-89-6
分子式	C10H13N5O5
分子量	283.24
EINECS号
相关类别	合成;Bases & Related Reagents;Labeling and Diagnostics Reagents;Nucleotides;Heterocycles
Mol文件	88847-89-6.mol
结构式

8-OH-脱氧鸟嘌呤 性质

8-OH-脱氧鸟嘌呤 用途与合成方法

生物活性

8-Hydroxy-2'-deoxyguanosine 是氧化应激和致癌反应的关键生物标志物。

靶点

体外研究

8-Hydroxy-2'-deoxyguanosine (8-OHdG) is a good biomarker for risk assessment of various cancers and degenerative diseases. The biomarker 8-Hydroxy-2'-deoxyguanosine (8-OHdG) or 8-oxodG has been a pivotal marker for measuring the effect of endogenous oxidative damage to DNA and as a factor of initiation and promotion of carcinogenesis. The biomarker has been used to estimate the DNA damage in humans after exposure to cancer-causing agents, such as tobacco smoke, asbestos fibers, heavy metals, and polycyclic aromatic hydrocarbons.

安全信息

MSDS信息

8-OH-脱氧鸟嘌呤 价格(试剂级)

8-OH-脱氧鸟嘌呤 上下游产品信息

上游原料

8-Benzyloxy-2'-deoxy-D-guanosine2'-脱氧鸟苷8-溴2‘-脱氧鸟苷