依来多辛 CAS#: 69-25-0

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依来多辛

用途靶点体外研究体内研究 用途与合成方法 MSDS 依来多辛价格(试剂级) 上下游产品信息

中文名称	依来多辛
中文同义词	依来多辛;麝香蛸素;醋酸依来多辛 ELEDOISINACETATE;醋酸依来多辛 69-25-0;醋酸依来多辛;ELEDOISIN ACETATE 醋酸依来多辛;章鱼唾腺精, >99%;章鱼唾腺精
英文名称	Eledoisin
英文同义词	eledonepeptide;ELEDOISIN;GLP-PRO-SER-LYS-ASP-ALA-PHE-ILE-GLY-LEU-MET-NH2;5-oxo-l-prolyl-l-prolyl-l-seryl-l-lysyl-l-aspartyl-l-alanyl-l-phenylalanyl-l-isoleucylglycyl-l-leucyl-l-methioninamide;PYR-PRO-SER-LYS-ASP-ALA-PHE-ILE-GLY-LEU-MET-NH2;PYR-PSKDAFIGLM-NH2;PGLU-PRO-SER-LYS-ASP-ALA-PHE-ILE-GLY-LEU-MET-NH2;ELEDOSIN
CAS号	69-25-0
分子式	C54H85N13O15S
分子量	1188.4
EINECS号	251-228-4
相关类别	多肽;医药原料药;医药原料;proteins;Peptide
Mol文件	69-25-0.mol
结构式

依来多辛 性质

依来多辛 用途与合成方法

用途

依来多辛是 NK2 和 NK3 受体的特异性激动剂。

靶点

NK2 and NK3 receptors.

体外研究

Eledoisin (Eledone peptide) increases the value recorded under basal conditions by 24.5±3.7%; this stimulation is significantly (P<0.01) lowered to 13.1±1.9% by the simultaneous presence of CP99994. The same protocol is also used to characterize the sensitivity of Eledoisin stimulation to 0.1 μM SR48968 or 0.1 μM SB222200. SR48968 significantly (P < 0.01) lower the stimulation by Eledoisin, while SB222200 has no effect. Eledoisin stimulation is reduced by CP99994 and SR48968, NK1 and NK2 antagonists, respectively.

体内研究

Eledoisin (Eledone peptide; 0.1-1 nmol/kg) injected into rats produces a biphasic cardiovascular response that consists of an initial fall of systemic blood pressure (8-15 mm Hg) followed by a rise (20-22 mm Hg). Intracerebroventricular injection of Eledoisin produces an enhancement of grooming and scratching behavior in mice.

安全信息

MSDS信息

依来多辛 价格(试剂级)

依来多辛 上下游产品信息