QL9 CAS#: 159646-83-0

微信扫码

QL9

生物活性靶点体外研究 用途与合成方法 MSDS QL9价格(试剂级) 上下游产品信息

中文名称	QL9
中文同义词	TCR识别抗原多肽
英文名称	QL9
英文同义词	QL9;L-Leucine, L-glutaminyl-L-leucyl-L-seryl-L-prolyl-L-phenylalanyl-L-prolyl-L-phenylalanyl-L-α-aspartyl-
CAS号	159646-83-0
分子式	C52H74N10O14
分子量	1063.22
EINECS号
相关类别
Mol文件	159646-83-0.mol
结构式

QL9 性质

QL9 用途与合成方法

生物活性

QL9 是针对2C T细胞受体 (TCR) 的高亲和力同种异体抗原。

靶点

TCR

体外研究

Mouse T cell clone 2C recognizes two different major histocompatibility (MHC) ligands, the self MHC K     ^b    and the allogeneic MHC L     ^d    . Two distinct peptides, SIY (SIYRYYGL) and QL9 (QLSPFPFDL), act as strong and specific agonists when bind to K     ^b    and L     ^d    , respectively. QL9 binding to MHC L     ^d    is influenced by the majority of peptide side chains, distributed across the entire length of the peptide. Findings with both systems, but QL9-L     ^d    in particular, suggest that many single-residue substitutions, introduced into peptides to improve their binding to MHC and thus their vaccine potential, could impair T cell reactivity due to their dual impact on TCR binding. T cell activation assays are performed to measure effects of peptide SIY and QL9 residues on T cell function.

安全信息

MSDS信息

QL9 价格(试剂级)

QL9 上下游产品信息