2-吲哚酮 CAS#: 59-48-3

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2-吲哚酮

应用生物活性体外研究 用途与合成方法 MSDS 2-吲哚酮价格(试剂级) 上下游产品信息 专题

中文名称	2-吲哚酮
中文同义词	2-吲哚酮;氧化吲哚;羟吲哚;2-吲哚酮(2-羟基吲哚);1,3-二氢-吲哚-2-酮;鄰胺苯乙酸內醯胺;2-羥吲哚;吲哚二酮
英文名称	Oxindole
英文同义词	OXINDOL;OXINDOLE;O-(AMINOPHENYL)ACETIC ACID LACTAM;TIMTEC-BB SBB004215;2-Oxo-2,3-dihydroindole;Indoline-2-one;NSC 274863;1,3-dihydro-2h-indol-2-on
CAS号	59-48-3
分子式	C8H7NO
分子量	133.15
EINECS号	200-429-5
相关类别	吲哚类;硼酸系列;吲哚;细胞生物学;苯基硼酸类及衍生物系列;医药中间体;有机原料-酮;分析试剂标准品;生物碱;杂环化合物;有机化工原料;化工中间体;杂质对照品;化工原料;blocks;IndolesOxindoles;Aromatic Phenylacetic Acids and Derivatives;Indoles and derivatives;Indoline & Oxindole;Indoles;Indole Derivatives;Heterocycle-Indole series;其他原料
Mol文件	59-48-3.mol
结构式

2-吲哚酮 性质

2-吲哚酮 用途与合成方法

应用

2-吲哚酮为酮类衍生物，可用作医药中间体。

生物活性

Oxindole (2-indolone, 2-Oxindole, Indolin-2-one)是芳香族杂环有机化合物，当剂量过量时，可引起镇静、肌无力、低血压和昏迷。

体外研究

Oxindole (Indolin-2-one) is a bicyclic structure consisting of a benzene ring fused to 2-pyrrolidone. Substituted indolinones can be referred as ‘privileged structures’ owing to their excellent binding affinity for many receptors and to the number of approved drugs containing this scaffold. Oxindole has been found in tissues and fluids of mammals as well as natural products produced by a range of plants, bacteria and invertebrates. 2-indolinone derivatives possess diverse range of pharmacological activities including anti-cancer, anti-HIV, anti-diabetic, antibacterial, antioxidant, kinase inhibitory, AChE inhibitory, anti-leishmanial, b3 adrenergic receptor agonistic, phosphatase inhibitory, analgesic, spermicidal, vasopressin antagonists, progesterone antagonists, neuroprotection, NMDA blocker and sleep inducing activities.

化学性质 

白色或微黄色结晶粉末，熔点121-124°C。

用途 

吲哚类似物； 显示药理活性。

安全信息

MSDS信息

2-吲哚酮 价格(试剂级)

2-吲哚酮 上下游产品信息

上游原料

2,6-二氯-N-甲酰苯胺1-(2,6-二氯苯基)-1,3-二氢-2H-吲哚-2-酮双氯芬酸钠2,6-二氯苯基异氰酸酯9(10H)-Acridinone, 4-chloro-2,6-二氯硝基苯2,6-二氯-N-苯基苯胺

下游产品

5-溴氧化吲哚5-乙酰基吲哚-2-酮10,15-二氢-5H-二吲哚并[3,2-A:3',2'-C]咔唑Semaxanib5-硼酸频那醇酯吲哚-2-酮1-甲基-2-吲哚啉酮