莰菲醇-3-O-芸香糖苷 CAS#: 17650-84-9

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莰菲醇-3-O-芸香糖苷

生物活性靶点体外研究体内研究 用途与合成方法 MSDS 莰菲醇-3-O-芸香糖苷价格(试剂级) 上下游产品信息

中文名称	莰菲醇-3-O-芸香糖苷
中文同义词	山柰酚-3-O-芸香糖苷(烟花苷,莰菲醇-3-O-芸香糖苷,莰非醇-3-O-芸香糖苷);山柰酚-3-O-芸香糖苷;莰菲醇-3-O-芸香糖苷;莰非醇-3-O-芸香糖苷;山柰酚-3-O-芸香糖苷(标准品);烟花苷;山柰酚-3-O-芸香糖苷, 来源于红花;烟花苷,莰菲醇-3-O-芸香糖苷,莰非醇-3-O-芸香糖苷
英文名称	KAEMPFEROL-3-O-RUTINOSIDE
英文同义词	KaeMpferol-3-O-rutinoside, Nicotiflorin;Nictoflorin (incorr;4H-1-Benzopyran-4-one,3-[[6-O-(6-deoxy-a-L-Mannopyranosyl)-b-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-;3,4′,5,7-Tetrahydroxyflavone 3-rhamnoglucoside;KaeMpferol-3-O-rutinosid, froM CarthaMus tinctorius;Kaempferol-3-O-rutinosid;Aempferol-3-O-rutinoside;NICOTIFLORIN
CAS号	17650-84-9
分子式	C27H30O15
分子量	594.52
EINECS号
相关类别	对照品;标准品;植物提取物;标准品-中药标准品;中药对照品;植提标准品;类黄酮;化学连接;对照品-中药对照品;黄酮;标准品 -中药标准品;标准品，对照品;黄金产品;Tetra-substituted Flavones;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol文件	17650-84-9.mol
结构式

莰菲醇-3-O-芸香糖苷 性质

莰菲醇-3-O-芸香糖苷 用途与合成方法

生物活性

Kaempferol-3-O-rutinoside (Nicotiflorin, Nikotoflorin, Kaempferol 3-O-β-rutinoside) 是从 Carthamus tinctorius 中提取的黄酮，可改变受伤神经元的形状和结构，减少凋亡细胞，下调 p-JAK2、p-STAT3、caspase-3 和 Bax 的表达，并降低Bax免疫反应性，并增加 Bcl-2 蛋白表达和免疫反应性。

靶点

体外研究

For primarily cultured neurons suffered 2 h hypoxia followed by 24 h reoxygenation, nicotiflorin significantly attenuates cell death and reduces LDH release. Morphological observation also directly confirms its protective effect on neuron. After total 4 h hypoxia and 12 h reoxygenation, eNOS activity, mRNA and protein levels in the primarily cultured rat cerebral blood vessel endothelial cells treated with nicotiflorin (25-100 g/mL) 2 h after onset of hypoxia are significantly higher than eNOS activity, mRNA and protein levels in the pure H-R cells and also higher than eNOS activity, mRNA and protein levels in cells cultured under normoxic conditions.

体内研究

At doses of 2.5, 5 and 10 mg/kg, nicotiflorin administered immediately after the onset of ischemia markedly reduces brain infarct volume and neurological deficits. Nicotiflorin (2.5-10 mg/kg) administered after onset of ischemia markedly reduces brain infarct volume by 24.5-63.2% and neurological deficits.

化学性质 

浅黄色针状结晶，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于槐米，红花。

用途 

山奈酚-3-O-芸香糖苷具有降血脂，活血化瘀的作用。

用途 

用于含量测定/鉴定/药理实验等。
药理药效:降血脂、善痴呆症状和记忆保护

安全信息

MSDS信息

莰菲醇-3-O-芸香糖苷 价格(试剂级)

莰菲醇-3-O-芸香糖苷 上下游产品信息