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伪赤藓霉素A烯醇醚
生物活性体内研究
| 中文名称 | 伪赤藓霉素A烯醇醚 |
|---|---|
| 中文同义词 | 伪赤藓霉素A烯醇醚;伪红霉素 A 烯醇醚;假红霉素 A 烯醇醚;红霉素杂质F[表红霉素 A 烯醇醚];红霉素杂质15;红霉素杂质F(EP);红霉素杂质06;琥乙红霉素EP杂质F |
| 英文名称 | LY 267108 |
| 英文同义词 | LY 267108;(2R,3R,6R,7S,8S,9R,10R)-7-[(2,6-Dideoxy-3-C-Methyl-3-O-Methyl-α-L-ribo-hexopyranosyl)oxy]-3-[(1R,2R)-1,2-dihydroxy-1-Methylbutyl]-2,6,8,10,12-pentaMethyl-9-[[3,4,6-trideoxy-3-(diMethylaMino)-β-D-xylo-hexopyranosyl]oxy]-4,13-dioxabicyclo[8.2.1]tridec-12-en-5-one;8,9-Anhydropseudo-erythroMycin A-6,9-heMiketal;(2R,3R,6R,7S,8S,9R,10R)-7-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy]-3-[(1R,2R)-1,2-dihydroxy-1-methylbutyl]-2,6,8,10,12-pentamethyl-9-[[3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl]oxy]-4,13-dioxabicyclo[8.2.1]tridec-12-en-5-one;NMIWBQUQCOMGHJ-XWVSLMRSSA-N;Erythromycin EP Impurity F/(2R,3R,6R,7S,8S,9R,10R)-3-((2R,3R)-2,3-dihydroxypentan-2-yl)-9-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-7-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-2,6;Erythromycin Impurit F:(pseudoerythromycin A enol ether);Erythromycin Impurity 15(Erythromycin EP Impurity F) |
| CAS号 | 105882-69-7 |
| 分子式 | C37H65NO12 |
| 分子量 | 715.91 |
| EINECS号 | |
| 相关类别 | 红霉素杂质;微生物代谢物;杂质对照品;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Chromatography;Drugs&Metabolites;Forensic and Veterinary Standards;Neat CompoundsAnalytical Standards;Pharmacology Standards |
| Mol文件 | 105882-69-7.mol |
| 结构式 |  |
伪赤藓霉素A烯醇醚 性质
| 熔点 | 127.0-130.0 °C |
|---|---|
| 沸点 | 810.7±65.0 °C(Predicted) |
| 密度 | 1.20±0.1 g/cm3(Predicted) |
| 储存条件 | −20°C |
| 溶解度 | DMF：可溶； DMSO：可溶；乙醇：可溶；甲醇：可溶 |
| 酸度系数(pKa) | 13.45±0.70(Predicted) |
伪赤藓霉素A烯醇醚 用途与合成方法
生物活性
Pseudoerythromycin A enol ether (LY267108) 是红霉素的降解产物。Pseudoerythromycin A enol ether 无明显抑菌活性。
体内研究
Pseudoerythromycin A enol ether (LY267108) increases lower esophageal sphincter (LES) pressure in cats.
安全信息
| WGK Germany | 3 |
|---|
MSDS信息
伪赤藓霉素A烯醇醚 上下游产品信息
下游产品
红霉素A肟
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