廿二碳四烯酸 CAS#: 28874-58-0

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廿二碳四烯酸

简介生物活性靶点体外研究 用途与合成方法 MSDS 廿二碳四烯酸价格(试剂级) 上下游产品信息 专题

中文名称	廿二碳四烯酸
中文同义词	7,10,13,16-二十二碳四烯酸;廿二碳四烯酸;廿二碳四烯酸 10MG;肾上腺酸(溶解于乙醇);二十二碳四烯酸(顺-7,10,13,16);顺式-7,10,13,16-二十二碳四烯酸;二十二碳四烯酸;肾上腺酸(乙醇溶液)
英文名称	ADRENIC ACID
英文同义词	CIS-7,10,13,16,19-DOCOSA-TETRAENOIC ACID;CIS-7,10,13,16-DOCOSA-TETRAENOIC ACID;DOCOSATETRAENOIC ACID;DOCOSA-7Z,10Z,13Z,16Z-PENTAENOIC ACID;DOCOSA-7Z,10Z,13Z,16Z-TETRAENOIC ACID;cis-7,10,13,16-Docosatetraenoic acid, C22:4n6;7Z,10Z,13Z,16Z-DOCOSATETRAENOIC ACID;ADRENIC ACID
CAS号	28874-58-0
分子式	C22H36O2
分子量	332.52
EINECS号
相关类别	脂肪酸;生化试剂;Unsaturated  fatty  acids  and  derivatives;DJ  -  DZUnsaturated  fatty  acids  and  derivatives;Alphabetic;D;Omega  6  fatty  acids  and  derivatives;Polyunsaturated
Mol文件	28874-58-0.mol
结构式

廿二碳四烯酸 性质

廿二碳四烯酸 用途与合成方法

简介

廿二碳四烯酸是一种不饱和脂肪酸，可由花生四烯酸通过五步制备得到。该类不饱和脂肪酸通常来源于鱼油中。

生物活性

Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) 是一种天然的多不饱和脂肪酸，主要存在于肾上腺，大脑，肾脏和脉管系统中。Adrenic Acid 可以调节肾上腺皮质血管的血管紧张度。Adrenic Acid 也是非酒精性脂肪肝疾病的炎症增强剂。

靶点

体外研究

Adrenic acid is produced via the elongation of arachidonic acid by ELOVL2 and 5. Interestingly, the hepatic level of free Adrenic Acid (22:4n6) is markedly higher in the CDAHFD-fed db/db mice than in the SD-fed db/db mice. In plasma, the difference in the adrenic acid level reaches statistical significance (p<0.001). It is also found that the concentrations of phospholipid species containing Adrenic Acid, such as PC or PE (40:4) (containing side chain 18:0/22:4), and LPC 22:4 (sn-1/sn-2), are also significantly increased. (sn-1/sn-2). The hepatic and plasma levels of Adrenic Acid, which is an omega 6 polyunsaturated fatty acid (PUFA), exhibit greater differences between the CDAHFD-fed db/db mice and the SD-fed db/db mice (8.6-fold higher vs. 1.6-fold higher in liver tissue, 5.3-fold higher vs. 2.2-fold higher in plasma) than those of well-known proinflammatory PUFA, such as Arachidonic Acid.

安全信息

MSDS信息

廿二碳四烯酸 价格(试剂级)

廿二碳四烯酸 上下游产品信息