MOUSE ANTI HUMAN VIMENTIN 抗体
描述宿主种属反应性偶联物验证的应用品牌示例背景简介 专题
| 中文名称 | MOUSE ANTI HUMAN VIMENTIN 抗体 |
|---|---|
| 中文同义词 | MOUSE ANTI HUMAN VIMENTIN 抗体 |
| 英文名称 | Mouse Anti Human Vimentin Antibody |
| 英文同义词 | MOUSE ANTI HUMAN VIMENTIN;Mouse Anti Human Vimentin Antibody |
| CAS号 | |
| 分子式 | |
| 分子量 | 0 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | Mol File |
| 结构式 |
MOUSE ANTI HUMAN VIMENTIN 抗体 性质
MOUSE ANTI HUMAN VIMENTIN 抗体 用途与合成方法
描述
Mouse Anti Human Vimentin Antibody
宿主
Mouse
种属反应性
Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.
偶联物
Unconjugated
验证的应用
EL, WB, IP, IH
品牌示例
Vimentin antibody AbD2701

Western blot analysis of whole cell lysates probed with vimentin antibody (MA00008) followed by detection with HRP conjugated Goat anti Human IgG F(ab)2 (1/2500, STAR126P) and visualized on the ChemiDoc MP with 2 second exposure. Arrow points to vimentin (molecular weight 54 kDa).
背景
Vimentin expression in human malignant glioma cells depends on cellular density, algorithms of drug delivery and chemo/radio treatment. Vimentin and detyrosinated microtubules provide structural support for the extensive microtentacles observed in detached tumor cells and a mechanism to promote successful metastatic spread. Primary colorectal carcinomas display aberrant expression of vimentin, and have activated Notch and TGFbeta signaling pathways. Vimentin is a strong arterial substrate for transglutaminases. Transglutaminase-mediated vimentin dimerization results in a novel unifying pathway by which vasodilatory and remodeling responses may be regulated. Ablation of vimentin expression inhibits migration and invasion of colon and breast cancer cell lines.
简介
MOUSE ANTI HUMAN VIMENTIN抗体是以HUMAN VIMENTIN为抗原以小鼠为宿主制得的免疫抗体,可以特异性结合HUMAN VIMENTIN。主要用于检测HUMAN VIMENTIN的Western Blot、IHC-P、IF、ELISA、Co-IP等多种免疫学实验。



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