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| 中文名: | N4-[2-(4-苯氧基苯基)乙基]-4,6-喹唑啉二胺;QNZ (EVP4593) |
| 中文别名: | N4-[2-(4-苯氧基苯基)乙基]-4,6-喹唑啉二胺 |
| 英文名称： | 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline |
| 英文别名： | N4-[2-(4-Phenoxyphenyl)ethyl]-4,6-quinazolinediamine; QNZ; |
| CAS No.: | 545380-34-5 |
| 分子式: | C22H20N4O |
| 分子量: | 356.42 |
| 性状: | Melting Point: 169-175°C |
| 储存: | Refrigerator, Under Inert Atmosphere |
| 安全术语: | |
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| 危险品标志: | |
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| 用途: | Aplications: QNZ is a novel inhibitor of NFkB which displays potent inhibitory effects on both NFKB transcriptional activation (IC50=11nM) and TNF-α production (IC50=7nM). It dose-dependently inhibited carragenin-induced edema formation in the rat paw model (1m |
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