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| 中文名: | 5-[(2,2-二氟-1,3-苯并二恶茂-5-基)亚甲基]噻唑烷-2,4-二酮;5-((2,2-二氟苯并[d][1,3]二氧杂环戊烯-5-基)亚甲基)噻唑烷-2,4-二酮 |
| 中文别名: | AS 604850; 5-[(2,2-二氟-1,3-苯并二恶茂-5-基)亚甲基]噻唑烷-2,4-二酮 |
| 英文名称： | AS-604850 |
| 英文别名： | 5-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethylene)-thiazolidine-2,4-dione ;PI3Kγ inhibitor;AS 604850 |
| CAS No.: | 648449-76-7 |
| 分子式: | C11H5F2NO4S |
| 分子量: | 285.22 |
| 性状: | 属性溶解性Soluble in DMSO (>10 mg/ml), water (<2 mg/ml), acetonitrile (6 mg/ml), methanol (9 mg/ml), and 100% ethanol.存贮条件储存温度 2-8°C描述产品介绍AS-604850是一种选择性的，ATP竞争性的PI3Kγ抑制剂，IC50为250 nM，作用于PI3Kγ比作用于PI3Kδ/β选择性高80倍以上，作用于PI3Kγ比作用于PI3Kα选择性高18倍。用途An ATP-competitive inhibitor of PI 3-kinase γ.生化机理AS-604850 is a potent, cell permeable and ATP-competitive inhibitor of PI 3-kinase γ (PI(3)Kγ). AS-604850 also exhibits selectivity over other PI 3-kinase isoforms. AS-604850 is an inhibitor of PI 3-kinase and PI 3-kinase p55 γ, PI 3-kinase p110 α and PI 3-kinase p85 α.包装A129517-5mg,A129517-25mg,A129517-100mg in glass bottle |
| 储存: | 储存温度 2-8°C |
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| 用途: | An ATP-competitive inhibitor of PI 3-kinase γ. |
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