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| 中文名: | LY2603618;N-[5-溴-4-甲基-2-[(2S)-2-吗啉甲氧基]苯基]-N'-(5-甲基-2-吡嗪基)脲 |
| 中文别名: | N-[5-溴-4-甲基-2-[(2S)-2-吗啉甲氧基]苯基]-N‘-(5-甲基-2-吡嗪基)脲;IC-83; LY 2603618 |
| 英文名称： | LY2603618 |
| 英文别名： | LY-2603618;N-[5-Bromo-4-methyl-2-[(2S)-2-morpholinylmethoxy]phenyl]-N‘-(5-methyl-2-pyrazinyl)urea;(S)-1-(5-bromo-4-methyl-2-(morpholin-2-ylmethoxy)phenyl)-3-(5-methylpyrazin-2-yl)urea |
| CAS No.: | 911222-45-2 |
| 分子式: | C18H22BrN5O3 |
| 分子量: | 436.3 |
| 性状: | 属性溶解性Soluble in water (<1 mg/ml) at 25 °C, DMSO (13 mg/ml) at 25 °C, and ethanol (<1 mg/ml) at 25 °C.存贮条件储存温度-20°C描述产品介绍Y2603618是一种选择性Chk1抑制剂，具有潜在的抗肿瘤活性。Phase 2。用途A selective Chk1 inhibitor.生化机理LY2603618 (IC-83) is a very selective checkpoint kinase 1 (Chk1) inhibitor with the potential for antitumor effects. Chk1 is an ATP-dependent serine-threonine kinase that is very important to the checkpoint monitoring system of DNA replication. |
| 储存: | 储存温度-20°C |
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| 用途: | A selective Chk1 inhibitor. |
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