磷酸异丙酯(单双酯混合物)
生物活性体外研究体内研究 用途与合成方法 MSDS 磷酸异丙酯(单双酯混合物)价格(试剂级) 上下游产品信息
| 中文名称 | 磷酸异丙酯(单双酯混合物) |
|---|---|
| 中文同义词 | 磷酸异丙酯(单双酯混合物);3-(4-羟基甲基)丙酸;3-(4-羟基-3-甲氧苯基)丙酸;3-(4-羟基-3-甲氧基苯基)丙酸,97%;氢化阿魏酸;3-(4-羟基-3-甲氧基苯基)丙酸;4-羟基-3-甲氧基苯基丙酸;二氢阿魏酸 |
| 英文名称 | 3-(4-HYDROXY-3-METHOXYPHENYL)PROPIONIC ACID |
| 英文同义词 | 3-(3-METHOXY-4-HYDROXYPHENYL)-PROPIONIC ACID;Benzenepropanoic acid, 4-hydroxy-3-methoxy-;3-Methoxyphloretic Acid;Dihydroconiferylic Acid;Shorbic Acid;β-3-Methoxy-4-hydroxyphenylpropionic acid;3-(4-HYDROXY-3-METHOXYPHENYL)PROPIONIC ACID 98%;3-(4-Hydroxy-3-methoxyphenyl)propionic acid >=96.0% (T) |
| CAS号 | 1135-23-5 |
| 分子式 | C10H12O4 |
| 分子量 | 196.2 |
| EINECS号 | 214-489-5 |
| 相关类别 | 小分子抑制剂;羧酸;小分子抑制剂，天然产物;杂质对照品;standard material,plant extracts;Inhibitors;Aromatics, Metabolites & Impurities;Aromatic Cinnamic Acids, Esters and Derivatives;Aromatics;Metabolites & Impurities |
| Mol文件 | 1135-23-5.mol |
| 结构式 |  |
磷酸异丙酯(单双酯混合物) 性质
| 熔点 | 87-93 °C |
|---|---|
| 沸点 | 120-130 °C(Press: 0.5 Torr) |
| 密度 | 1.259±0.06 g/cm3(Predicted) |
| 溶解度 | 溶于二甲基亚砜和甲醇。 |
| 酸度系数(pKa) | 4.73±0.10(Predicted) |
| 形态 | 粉末晶体 |
| 颜色 | 白色至浅黄色至浅橙色 |
| BRN | 2110370 |
| LogP | 0.810 (est) |
| CAS 数据库 | 1135-23-5(CAS DataBase Reference) |
磷酸异丙酯(单双酯混合物) 用途与合成方法
生物活性
Dihydroferulic acid (Hydroferulic acid) 是姜黄素的主要代谢产物之一，具有抗氧化/清除自由基的活性，IC50 值为 19.5 μM。Dihydroferulic acid 是人类肠道菌群的代谢产物，也是香草酸的前体物质。
体外研究
Uptake of hydroxycinnamic acids by control, organic anion transporter 1 (OAT1), OAT2, OAT3, and OAT4 over expressing 293H cells. In 293H control cells, there was significant uptake of Dihydroferulic acid. The uptake of Dihydroferulic acid is also enhanced ~2-fold in the OAT1-expressing cells.
体内研究
Assessing the influence of an 11 weeks intervention with a resistant starch-enriched whole grain diet (HI-RS-WG, 25% RS) compared to a WG control diet (LOW-RS-WG, 6.9% RS) on serum profile of polyphenols (PPs) in 20 Zucker Diabetic Fatty rats. Five PPs were identified and quantified in serum samples of rats belonging to both intervention groups. HI-RS-WG rats had 2.6 folds higher serum concentrations of total PPs than LOW-RS-WG rats. An explorative data reduction approach, based on the Principal Component Analysis identified two principal components related to the gut microbiota fermentation and food intake, respectively. Results showed that the abundance of hippuric acid and Dihydroferulic acid in HI-RS-WG rats was explained by the stronger gut microbiota fermentation in those rats than in LOW-RS-WG rats.
安全信息
| 危险品标志 | Xn |
|---|---|
| 危险类别码 | 22-36/37/38 |
| 安全说明 | 26-36 |
| WGK Germany | 2 |
| 危险等级 | IRRITANT |
| 海关编码 | 29189900 |
MSDS信息
| 提供商 | 语言 |
|---|---|
SigmaAldrich | 英文 |
ALFA | 中文 |
ALFA | 英文 |
磷酸异丙酯(单双酯混合物) 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/08/19 | A12069 | 3-(4-羟基-3-甲氧基苯基)丙酸, 97% 3-(4-Hydroxy-3-methoxyphenyl)propionic acid, 97% | 1135-23-5 | 1g | 830元 |
| 2024/08/19 | A12069 | 3-(4-羟基-3-甲氧基苯基)丙酸, 97% 3-(4-Hydroxy-3-methoxyphenyl)propionic acid, 97% | 1135-23-5 | 5g | 3197元 |
磷酸异丙酯(单双酯混合物) 上下游产品信息
下游产品
四氢姜黄素
