Human FPRL1/FPR2 Alexa Fluor 700 MAb (Clone 304405) 100 TESTS

• Species Reactivity

  Human

• Specificity

  Stains FPRL1 transfectants but not irrelevant transfectants. It also stains monocytes and granulocytes.

• Source

  Monoclonal Mouse IgG    _2B Clone # 304405

• Purification

  Protein A or G purified from hybridoma culture supernatant

• Immunogen

  NS0 mouse myeloma cell line transfected with human FPRL1    
  Met1-Met351    
  Accession # P25090

• Formulation

  Supplied in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 700

Applications

• 
  

  Recommended    
  Concentration

  Sample

• Flow Cytometry

  5 µL/10    ⁶ cells

  See below

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Data Examples

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Protect from light.    Do not freeze.    

• 12 months from date of receipt, 2 to 8 °C as supplied.

Background: FPRL1/FPR2

FPRL1 is a 7TM protein expressed on mononuclear phagocytes and microglial cells. It interacts with formyl peptides to attract phagocytes to sites of infection and promote inflammatory reactions. FPRL1 also interacts with amyloid beta peptides and has been implicated in phagocyte attraction to sites of amyloid plaques in Alzheimer’s disease.

• Long Name:

  Formyl Peptide Receptor-like 1

• Entrez Gene IDs:

  2358 (Human); 14289 (Mouse)

• Alternate Names:

  ALXR; FMLP-R-I; FMLP-R-II; FMLPX; formyl peptide receptor 2; Formyl peptide receptor-like 1RFP; FPR2; FPR2A; FPRH1FMLP-related receptor I; FPRL1; FPRL1LXA4 receptor; HM63; HM63FPRH2; lipoxin A4 receptor (formyl peptide receptor related); Lipoxin A4 receptor; LXA4 Receptor; LXA4RFMLP-R-I; N-formyl peptide receptor 2; RFP