7(S)-Maresin 1 25 µg_行业前沿_产品

应用； An epimer of the active 7(R)-MaR1

CAS号码: 1268720-66-6

纯度: ≥95%

分子量: 360.5

分子式: C₂₂H₃₂O₄

Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.

* 参考分析证明大量特定数据 (包括水含量).

介绍技术信息安全信息安全技术说明书和分析证明书

Docosahexaenoic acid (DHA) is an ω-3 fatty acid that is abundant in the brain and the retina and is known to be important in early development. Maresin 1 (7(R)-MaR1) is a 7,14-DHA formed from 14S-hydroperoxy DHA supplied exogenously to resident peritoneal murine macrophages activated with zymosan A. It potently reduces infiltration of neutrophils into the murine peritoneum in zymosan A-induced peritonitis when given intravenously (0.2 ng) and significantly increases phagocytosis of FITC-labeled zymosan A by isolated mouse macrophages (0.1-100 nM). 7(S)-MaR1 is an epimer of the active 7(R)-MaR1.

参考文献

1. Serhan, C.N., et al. 2009. J. Exp. Med. 206: 15-23. PMID: 19103881
2. Wu, T.C. and Chen, P.H. 2009. Pediatr Neonatol. 50: 135-142. PMID: 19750886
3. Su, H.M. 2010. J. Nutr. Biochem. 21: 364-373. PMID: 20233652

物理状态 :

Liquid

溶解度 :

Soluble in DMSO (~50 mg/ml), DMF (~50 mg/ml), and PBS,pH 7.2 (~0.05 mg/ml).

保存 :

Store at -80° C

仅供科研使用。不可用于诊断或治疗。

运输 :

UN 1170, Class 3, Packing group II

SMILES :

C(CC)=CCC=CC[C@H](C=CC=CC=C[C@H](CC=CCCC(=O)O)O[H])O[H]