Introduction
Thecurrentcryo-CLEMworkflowislaborious,requiresexpertusersandhasalowyield.Integratingafluorescencelightmicroscope(FLM)intoaFIB/SEMsystemdirectlyreducesthecomplexityoftheworkflow.Thisdecreasesthechancetodamage,contaminateordevitrifyyoursampleandincreasestheefficiencyoftheworkflow.
METEORremovestheneedfortransportingyoursamplesforcryo-CLEMbetweenplatformsbyintegratingaFLMwithyourcryo-FIB/SEM.Itiseasilyretrofittableandadaptabletoyourexistingworkflowandcryo-stage.
BenefitsIntegrationminimizestransferstepsByintegratinganFLMintoyourFIB/SEMmanytransferstepsareremoved,reducingtheriskofdamage,devitrificationorcontaminationofyoursample.IncreaseyieldCurrently,theyieldofthecryo-CLEMworkflowisaslowas20%,METEORwillincreasetheyieldbyminimizingcomplicatedtransfersteps.IncreasethroughputofsamplesBysimplifyingtheworkflowMETEORwillincreasethethroughputofthesamplepreparationforcryo-ETandultimatelyallowsforahigherefficiencyintheanalysisofbiologicalstructurestobeachieved.LesssampledamageLesssampledamagetranslatesintolesscryo-TEMtimebeingspentonsubstandardsamples,resultinginalowercostpersampleanalysed.ReducecostsReducespurchaseandmaintenancecostsbyabolishingtheneedforaseparatecryo-FLMsystem.
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