详细说明
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| Description | |
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| Catalogue Number | ECM440 |
| Brand Family | Chemicon® |
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| Description | β Integrin Screening Kit |
| Overview | Chemicon Investigator Kits for Integrin Research are a cost-effective source of reagents for all investigators involved with this expanding field of study. The b Integrin Screening Investigator Kit is designed for the screening of beta integrin family members. Integrins belong to a large family of cell surface proteins commonly referred to as glycoproteins. Integrins are composed of noncovalently associated alpha and beta subunits which make up heterodimers: the larger termed alpha chain and the smaller beta chain. At least 16 alpha subunits and 8 beta subunits are expressed, which can give rise to 22 different integrins. Integrins are thought to play critical roles in cell migration, differentiation, and survival. There is now considerable evidence that these transmembrane receptors play an important role in the regulation of gene expression and signal transduction. Excellent reviews of integrin structure, function, and ligand specificity may be found in: Hynes, R. 1992. Cell 69:11-25; Kramer, R. 1993. "Integrin Structure and Ligand Specificity in Cell-Matrix Interactions" in Molecular and Cellular Aspects of Basement Membranes. Academic Press. Chemicon offers the Beta Integrin Screening Investigator Kit for studies of human beta integrin subunits. All kit reagents are also available in larger sizes. The reagents in this kit are not application specific but rather may be used in a variety of procedures, depending upon the needs of the individual investigator. . |
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| Presentation | Chemicon's Beta Integrin Screening Kit (ECM440) contains monoclonals to beta1, beta2, beta3, beta4, and polyclonal beta5. 20 μg of each monoclonal and 20 μL of polyclonal is included in this economical kit. All components may also be purchased in larger sizes. |
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| Storage Conditions | Store antibodies at -20°C. Important Note: Due to the small volumes contained within the kit, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge before opening to dislodge any liquid entrapped in the container's cap during shipment. |
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| Material Size | 1 kit |
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