• Species Reactivity

  Rat

• Specificity

  Detects rat MuSK in direct ELISAs and Western blots.

• Source

  Monoclonal Mouse IgG    ₁ Clone # 78020

• Purification

  Protein A or G purified from hybridoma culture supernatant

• Immunogen

  Mouse myeloma cell line NS0-derived recombinant rat MuSK    
  Glu22-Thr494 (predicted)    
  Accession # Q62838

• Formulation

  Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

• Label

  Unconjugated

Applications

• Recommended    
  Concentration

  Sample

• Western Blot

  1 µg/mL

  Recombinant Rat MuSK

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Reconstitution

  Reconstitute at 0.5 mg/mL in sterile PBS.

• Shipping

  The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

• Stability & Storage

  Use a manual defrost freezer and avoid repeated freeze-thaw cycles.    

• 12 months from date of receipt, -20 to -70 °C as supplied.

• 1 month, 2 to 8 °C under sterile conditions after reconstitution.

• 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: MuSK

MuSK is a receptor tyrosine kinase expressed in muscle. It binds the heparin sulfate proteoglycan agrin to promote acetylcholine receptor clustering.

• Long Name:

  Muscle-specific Receptor Tyrosine Kinase

• Entrez Gene IDs:

  4593 (Human); 81725 (Rat)

• Alternate Names:

  EC 2.7.10; EC 2.7.10.1; MGC126323; MGC126324; muscle, skeletal, receptor tyrosine kinase; MuSK; skeletal receptor tyrosine-protein kinase