详细说明
Species Reactivity
Human
Specificity
Detects human CEACAM‑8/CD66b in direct ELISAs.
Source
Recombinant Monoclonal Mouse IgG 1 Clone # 913542
Purification
Protein A or G purified from cell culture supernatant
Immunogen
E. coli-derived recombinant human CEACAM-8/CD66b
Gln35-His141
Accession # P31997Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Biotin
Applications
Recommended
ConcentrationSample
Flow Cytometry
10 µL/10 6 cells
See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. are available in the Technical Information section on our website.
Data Examples
Flow Cytometry | Detection of CEACAM‑8/CD66b in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human CEACAM‑8/CD66b Biotinylated Monoclonal Antibody (Catalog # FAB4246B, filled histogram) or isotype control antibody (Catalog # , open histogram), followed by Streptavidin-Phycoerythrin (Catalog # ). View our protocol for . |
Preparation and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Do not freeze.
12 months from date of receipt, 2 to 8 °C as supplied.
Background: CEACAM-8/CD66b
CEACAM-8 (Carcinoembryonic Antigen-related Cell Adhesion Molecule 8) also known as CD66b, CD67 and NCA-95, is a 90 kDa member of the CEACAM subfamily of the CEA family of proteins. It is expressed by neutrophils and eosinophils, and serves as a binding partner for CEACAM-6 and Galectin-3. Mature human CEACAM-8 is a 287 amino acid GPI-linked glycoprotein. It contains one V-type and two C2-type Ig-like domains. No definitive rodent CEACAM-8 has been reported.
Long Name:
Carcinoembryonic Antigen-related Cell Adhesion Molecule 8
Entrez Gene IDs:
1088 (Human)
Alternate Names:
Carcinoembryonic antigen CGM6; carcinoembryonic antigen gene family member 6; carcinoembryonic antigen-related cell adhesion molecule 8; CD66b antigen; CD66b; CD67 antigen; CD67; CEACAM8; CEACAM-8; CGM6; NCA-95; Non-specific cross-reacting antigen NCA-95