• Species Reactivity

  Human

• Specificity

  Detects human Endorepellin/Perlecan in direct ELISAs and Western blots.

• Source

  Monoclonal Mouse IgG    ₁ Clone # 268908

• Purification

  Protein A or G purified from hybridoma culture supernatant

• Immunogen

  Mouse myeloma cell line NS0-derived recombinant human Endorepellin/Perlecan    
  Arg3684-Ser4391 (Ser4003Thr)    
  Accession # P98160

• Formulation

  Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

• Label

  Unconjugated

Applications

• Recommended    
  Concentration

  Sample

• Western Blot

  1 µg/mL

  Recombinant Human Endorepellin/Perlecan

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Reconstitution

  Reconstitute at 0.5 mg/mL in sterile PBS.

• Shipping

  The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

• Stability & Storage

  Use a manual defrost freezer and avoid repeated freeze-thaw cycles.    

• 12 months from date of receipt, -20 to -70 °C as supplied.

• 1 month, 2 to 8 °C under sterile conditions after reconstitution.

• 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Endorepellin/Perlecan

Endorepellin is the C-terminal domain of the heparan sulfate proteoglycan perlecan, which is a modular protein found in basement membranes. Endorepellin is an inhibitor of angiogenesis that blocks endothelial cell adhesion to fibronectin and type I collagen.

• Entrez Gene IDs:

  3339 (Human)

• Alternate Names:

  basement membrane-specific heparan sulfate proteoglycan core protein; endorepellin (domain V region); Endorepellin; heparan sulfate proteoglycan 2; HSPG; HSPG2; perlecan proteoglycan; Perlecan; PLCSchwartz-Jampel syndrome 1 (chondrodystrophic myotonia); PRCAN; SJA; SJS; SJS1