• Species Reactivity

  Human

• Specificity

  Detects human MyD88 in direct ELISAs. In direct ELISAs, no cross-reactivity with mouse MyD88 is observed.

• Source

  Monoclonal Rat IgG2b Clone # 316628

• Immunogen

  E. coli-derived recombinant human MyD88    
  Met1-Pro296    
  Accession # Q99836

• Formulation

  Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 750

Applications

• Recommended    
  Concentration

  Sample

• Intracellular Staining by Flow Cytometry

  0.25-1 µg/10    ⁶ cells

  Raji human Burkitt's lymphoma cell line fixed with paraformaldehyde and permeabilized with saponin

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: MyD88

Myeloid Differentiation primary response gene 88 (MyD88) contains a cytoplasmic Toll/interleukin 1 receptor (TIR) and functions as an adaptor protein in Toll-like receptor signaling. It is expressed in many adult tissues including heart, kidney and liver tissue and in monocyte, T, B, NK and dendritic cells.

• Long Name:

  Myeloid Differentiation Primary Response Gene 88

• Entrez Gene IDs:

  4615 (Human); 17874 (Mouse)

• Alternate Names:

  MyD88; MYD88D; myeloid differentiation primary response gene (88); myeloid differentiation primary response protein MyD88