• Species Reactivity

  Human

• Specificity

  Stains human Claudin-6 transfected cells but not irrelevant transfectants.

• Source

  Monoclonal Mouse IgG2b Clone # 342927

• Immunogen

  NS0 mouse myeloma cell line transfected with human Claudin-6    
  Met1-Val220    
  Accession # P56747

• Formulation

  Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 750

Applications

• Recommended    
  Concentration

  Sample

• Flow Cytometry

  0.25-1 µg/10    ⁶ cells

  HEK293 human embryonic kidney cell line

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: Claudin-6

Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively.

• Entrez Gene IDs:

  9074 (Human); 54419 (Mouse); 287098 (Rat)

• Alternate Names:

  claudin 6; Claudin6; Claudin-6; CLDN6; Skullin 2; skullin