• Species Reactivity

  Human

• Specificity

  Detects human STAMP2-transfected NS0 cells but not irrelevant transfectants in flow cytometry.    
   

• Source

  Monoclonal Mouse IgG2b Clone # 418714

• Immunogen

  NS0 mouse myeloma cell line transfected with human STAMP2    
  Met1-His459    
  Accession # EAW76907

• Formulation

  Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 750

Applications

• Recommended    
  Concentration

  Sample

• Flow Cytometry

  0.25-1 µg/10    ⁶ cells

  Human STAMP2 transfected HEK293 human cell line

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: STAMP2/STEAP4

Human STAMP2, also called Steap4 or TIARP (TNF-alpha -induced adipose-related protein), is a 55 kDa, 459 aa, 6-transmembrane (TM) member of the Steap family of metalloreductases. It is induced by androgens in androgen-regulated prostate cells, and is up‑regulated during adipocyte differentiation by TNF-alpha. Full-length human and mouse STAMP2 share 80% aa identity. A 283 aa variant lacks a portion of the oxidoreductase domain and three TM domains. STAMP2 is present in the Golgi complex and early endosomes in addition to the cell surface.

• Long Name:

  Six Transmembrane Protein of Prostate 2

• Entrez Gene IDs:

  79689 (Human); 117167 (Mouse)

• Alternate Names:

  EC 1.16.1; EC 1.16.1.-; FLJ23153; Six-transmembrane epithelial antigen of prostate 4; SixTransMembrane protein of prostate 2; STAMP2; STAMP2DKFZp666D049; STEAP family member 4; STEAP4; TIARP; TIARPsix transmembrane prostate protein 2; TNFAIP9; Tumor necrosis factor, alpha-induced protein 9metalloreductase STEAP4; tumor necrosis-alpha-induced adipose-related protein