• Species Reactivity

  Human

• Specificity

  Detects human GPRC5C in direct ELISAs.

• Source

  Monoclonal Mouse IgG2a Clone # 577315

• Immunogen

  NS0 mouse myeloma cell line transfected with recombinant human GPRC5C    
  Accession # Q9NQ84

• Formulation

  Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 750

Applications

• Recommended    
  Concentration

  Sample

• Flow Cytometry

  0.25-1 µg/10    ⁶ cells

  PC‑3 human prostate cancer cell line

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: GPRC5C

G-protein coupled receptor family C group 5 member C (GPRC5C), also known as Retinoic acid induced gene 3 (RAIG-3), is an approximately 50 kDa protein with seven transmembrane segments and one site of potential N-linked glycosylation. It is predominantly expressed in the stomach, kidney, liver, pancreas, and prostate. Human GPRC5C shares 88% and 90% amino acid sequence identity with mouse and rat GPRC5C, respectively.

• Long Name:

  G Protein-coupled Receptor, Family C, Group 5, Member C

• Entrez Gene IDs:

  55890 (Human)

• Alternate Names:

  G protein-coupled receptor, family C, group 5, member C; GPRC5C; MGC131820; RAIG3; RAIG-3G-protein coupled receptor family C group 5 member C; RAIG3orphan G-protein coupled receptor; retinoic acid responsive gene protein; Retinoic acid-induced gene 3 protein