• Species Reactivity

  Mouse

• Specificity

  Detects mouse Integrin beta 7 extracellular domain in direct ELISAs.

• Source

  Monoclonal Rat IgG2a Clone # 332418

• Immunogen

  Chinese hamster ovary cell line CHO-derived recombinant mouse Integrin beta 7    
  Glu20-His722    
  Accession # P26011

• Formulation

  Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 750

Applications

• Recommended    
  Concentration

  Sample

• Flow Cytometry

  0.25-1 µg/10    ⁶ cells

  Mouse lymph node single‑cell suspension

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: Integrin beta 7

Integrin beta 7 associates with the integrin alpha 4 or alpha E subunits to form heterodimers to interact with fibronectin, VCAM, MAdCAM or E-Cadherin. It is highly expressed in leukocytes and is involved in localization of leukocytes at mucosal sites.

• Entrez Gene IDs:

  3695 (Human); 16421 (Mouse); 25713 (Rat)

• Alternate Names:

  Gut homing receptor beta subunit; integrin beta 7 subunit; Integrin beta 7; integrin beta-7; integrin, beta 7; ITGB7