• Species Reactivity

  Mouse

• Specificity

  Detects mouse Urotensin-II R.  Stains mouse Urotensin-II R transfectants but not irrelevant transfectants in flow cytometry.

• Source

  Monoclonal Rat IgG2b Clone # 443707

• Immunogen

  Mouse Urotensin-II R synthetic peptide

• Formulation

  Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 750

Applications

• Recommended    
  Concentration

  Sample

• Flow Cytometry

  0.25-1 µg/10    ⁶ cells

  HEK293 human embryonic kidney cell line transfected with mouse Urotensin-II R and eGFP

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Stability & Storage

  Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: Urotensin-II R

Urotensin-II R (UR2R) belongs to the G protein-coupled receptor 1 family. UR2R is a high affinity receptor for urotensin-2 and urotensin-2B. The activity of UR2R is mediated by a G protein that activates a phosphatidylinositol-calcium second messenger system. It is most abundantly expressed in the heart and pancreas. Human UR2R has been correlated with cortico-adrenal carcinoma proliferation.

• Long Name:

  Urotensin-II Receptor

• Entrez Gene IDs:

  2837 (Human); 217369 (Mouse); 57305 (Rat)

• Alternate Names:

  G protein-coupled receptor 14; GPR14; G-protein coupled receptor 14; UR-2-R; UR-II-R; urotensin 2 receptor; urotensin II receptor; urotensin-2 receptor; Urotensin-II R; UrotensinIIR; Urotensin-IIR; UTR; UTR2; UTS2R