• Species Reactivity

  Human

• Specificity

  Detects human Porimin in direct ELISAs and Western blots.

• Source

  Monoclonal Mouse IgG2b Clone # 297617

• Immunogen

  Chinese hamster ovary cell line CHO-derived recombinant human Porimin    
  His27-Ser149    
  Accession # AAG21694

• Formulation

  Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 750

Applications

• Recommended    
  Concentration

  Sample

• Flow Cytometry

  0.25-1 µg/10    ⁶ cells

  Jurkat human acute T cell leukemia cell line

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: Porimin

Porimin is a widely expressed mucin-related transmembrane glycoprotein. Cross-linking of Porimin leads to membrane disruption and cell death.

• Long Name:

  Pro-Oncosis Receptor Inducing Membrane Injury

• Entrez Gene IDs:

  114908 (Human)

• Alternate Names:

  KCT3; KCT-3; KCT3keratinocytes associated transmembrane protein 3; Keratinocytes-associated transmembrane protein 3; Porimin; PORIMINporimin; pro oncosis receptor inducing membrane injury; Pro-oncosis receptor inducing membrane injury; serine/threonine-rich receptor; TMEM123; transmembrane protein 123PORMIN