• Species Reactivity

  Human

• Specificity

  Recognizes human CD94 both in its homodimeric form and as a heterodimer with either NKG2A or NKG2C.

• Source

  Monoclonal Mouse IgG1 Clone # 131412

• Immunogen

  BaF3 mouse pro-B cell line transfected with human CD94 and NKG2A

• Formulation

  Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 750

Applications

• Recommended    
  Concentration

  Sample

• Flow Cytometry

  0.25-1 µg/10    ⁶ cells

  Human whole blood CD56    ⁺ natural killer cells

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: CD94

The type-II transmembrane glycoprotein CD94 covalently associates with C-type lectins of the NKG2 family to yield heterodimers important in NK cell recognition of class I MHC molecules. CD94/NKG2A complexes are also found on a subset of CD8+ T cells. Expression of CD94/NKG2 heterodimers may regulate cell survival and effector functions. There are two alternatively spliced variants of CD94 that differ by 31 amino acids encoded by exon 2

• Entrez Gene IDs:

  3824 (Human); 16643 (Mouse)

• Alternate Names:

  CD94 antigen; CD94; CD94natural killer cells antigen CD94; Killer cell lectin-like receptor subfamily D member 1; killer cell lectin-like receptor subfamily D, member 1; KLRD1; KP43; NK cell receptor