• Species Reactivity

  Mouse

• Specificity

  Detects mouse IGSF2/CD101.

• Source

  Monoclonal Rat IgG2a Clone # 307707

• Immunogen

  Chinese hamster ovary cell line CHO-derived recombinant mouse IGSF2/CD101    
  Gln21-Tyr1033    
  Accession # A8E0Y8

• Formulation

  Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

• Label

  Alexa Fluor 750

Applications

• Recommended    
  Concentration

  Sample

• Flow Cytometry

  0.25-1 µg/10    ⁶ cells

  Mouse peripheral blood GR‑1    ⁺ granulocytes

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Preparation and Storage

• Shipping

  The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

• Stability & Storage

  Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IGSF2/CD101

IGSF2, also known as CD101, is an Ig-superfamily transmembrane protein. It is expressed on dendritic cells, Langerhans cells, granulocytes, and activated T cells. IGSF2 ligation is involved in T cell activation. Polymorphisms in IGSF2 are associated with susceptibility to type I diabetes. The extracellular domains of mouse and human IGSF2 share 70% amino acid sequence identity.

• Long Name:

  Immunoglobulin Superfamily, Member 2

• Entrez Gene IDs:

  9398 (Human); 630146 (Mouse)

• Alternate Names:

  CD101 antigen; CD101 molecule; CD101; Cell surface glycoprotein V7; EWI101; EWI-101; Glu-Trp-Ile EWI motif-containing protein 101; IGSF2; Leukocyte Surface Protein; member 2; V7