• Species Reactivity

  Mouse

• Specificity

  Detects mouse Urotensin-II R.  Stains mouse Urotensin-II R transfectants but not irrelevant transfectants in flow cytometry.

• Source

  Monoclonal Rat IgG    _2B Clone # 443707

• Purification

  Protein A or G purified from hybridoma culture supernatant

• Immunogen

  Mouse Urotensin-II R synthetic peptide

• Formulation

  Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

• Label

  Unconjugated

Applications

• 
  

  Recommended    
  Concentration

  Sample

• Flow Cytometry

  0.25 µg/10    ⁶ cells

  See below

• 
  

• CyTOF-ready

  Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Data Examples

Preparation and Storage

• Reconstitution

  Reconstitute at 0.5 mg/mL in sterile PBS.

• Shipping

  The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

• Stability & Storage

  Use a manual defrost freezer and avoid repeated freeze-thaw cycles.    

• 12 months from date of receipt, -20 to -70 °C as supplied.

• 1 month, 2 to 8 °C under sterile conditions after reconstitution.

• 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Urotensin-II R

Urotensin-II R (UR2R) belongs to the G protein-coupled receptor 1 family. UR2R is a high affinity receptor for urotensin-2 and urotensin-2B. The activity of UR2R is mediated by a G protein that activates a phosphatidylinositol-calcium second messenger system. It is most abundantly expressed in the heart and pancreas. Human UR2R has been correlated with cortico-adrenal carcinoma proliferation.

• Long Name:

  Urotensin-II Receptor

• Entrez Gene IDs:

  2837 (Human); 217369 (Mouse); 57305 (Rat)

• Alternate Names:

  G protein-coupled receptor 14; GPR14; G-protein coupled receptor 14; UR-2-R; UR-II-R; urotensin 2 receptor; urotensin II receptor; urotensin-2 receptor; Urotensin-II R; UrotensinIIR; Urotensin-IIR; UTR; UTR2; UTS2R