• Species Reactivity

  Human

• Specificity

  Detects human SLC14A1 in direct ELISAs.

• Source

  Monoclonal Mouse IgG    _2B Clone # 888418

• Purification

  Protein A or G purified from hybridoma culture supernatant

• Immunogen

  NS0 mouse myeloma cell line transfected with human SLC14A1    
  Accession # Q13336

• Formulation

  Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

• Label

  Unconjugated

Applications

• 
  

  Recommended    
  Concentration

  Sample

• Flow Cytometry

  2.5 µg/10    ⁶ cells

  See below

• 
  

• CyTOF-ready

  Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

• 
  

Please Note: Optimal dilutions should be determined by each laboratory for each application.  are available in the Technical Information section on our website.

Data Examples

Preparation and Storage

• Reconstitution

  Reconstitute at 0.5 mg/mL in sterile PBS.

• Shipping

  The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

• Stability & Storage

  Use a manual defrost freezer and avoid repeated freeze-thaw cycles.    

• 12 months from date of receipt, -20 to -70 °C as supplied.

• 1 month, 2 to 8 °C under sterile conditions after reconstitution.

• 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: SLC14A1

Urea transporter 1, designated Solute Carrier family 14 member 1 (SLC14A1) is a 43-54 kDa multipass urea transporter mainly expressed in erythrocytes, but also found in kidney, mesenchymal stem cells, and some carcinomas. It contains an epitope identified as the Kidd (JK) blood group antigen. The antigenic forms differ at only one amino acid (aa); Asp280 represents Jk(a) and Asn280 represents Jk(b). SLC14A1 Isoform 2 (445 aa) contains an extended N-terminus as compared to Isoform 1 (389 aa). Human SLC14A1 shares 83% and 81% aa sequence identity with mouse and rat SLC14A1, respectively.

• Long Name:

  Solute Carrier Family 14 (Urea Transporter), Member 1 (Kidd Blood Group

• Entrez Gene IDs:

  6563 (Human); 108052 (Mouse); 54301 (Rat)

• Alternate Names:

  FLJ33745; HsT1341; HUT11; JK; JKFLJ41687; RACH1; RACH2; SLC14A1; solute carrier family 14 (urea transporter), member 1 (Kidd blood group); Solute carrier family 14 member 1; truncated urea transporter; urea transporter 1; urea transporter JK glycoprotein; Urea transporter, erythrocyte; urea transporter-B1; UT1; UT1UT-B1; UT-B1; UTE; UTEblood group Kidd urea transporter