别名:   Fibroblast Growth Factor-7 HBGF-7 Keratinocyte Growth Factor

产品名称

Biochem/physiol Actions

KGF/FGF-7 is one of 23 known members of the FGF family. Recombinant human KGF/FGF-7 is an 18.9 kDa protein consisting of 163 amino acid residues.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in 1x PBS to a concentration of 0.5-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a stabilizer (example 5% Trehalose) and store in working aliquots at -20°C to -80°C.

Physical form

Lyophilized from 15 mM Sodium Phosphate pH 7.0 + 0.25 M NaCl.

General description

KGF/FGF-7 is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. KGF/FGF-7 is a mitogen factor specific for epithelial cells and keratinocytes. KGF/FGF-7 signals through FGFR 2b. KGF/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing. Recombinant human KGF/FGF-7 is an 18.9 kDa protein consisting of 163 amino acid residues.

Sequence

MCNDMTPEQM ATNVNCSSPE RHTRSYDYME GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MKNNYNIMEI RTVAVGIVAI KGVESEFYLA MNKEGKLYAK KECNEDCNFK ELILENHYNT YASAKWTHNG GEMFVALNQK GIPVRGKKTK KEQKTAHFLP MAIT

性质

recombinant	expressed in E. coli
assay	≥95% (HPLC)
	≥95% (SDS-PAGE)
form	lyophilized
mol wt	mol wt 18.9 kDa
impurities	<0.1 EU/μg endotoxin, tested
suitability	cell culture tested
UniProt accession no.	P21781
shipped in	wet ice
storage temp.	?20°C
Gene Information	human ... FGF7(2252)