产品名称

Biochem/physiol Actions

IL-17F, a member of the IL-17 family of structurally related cytokines, has been shown to stimulate proliferation and activation of T-cells and PBMCs. Recombinant murine IL-17F is a disulfide-linked homodimer of 30 kDa, consisting of two 134 amino acid residue chains.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Physical form

Lyophilized from 10 mM Sodium Acetate, pH 5.0.

General description

IL-17F, a member of the IL-17 family of structurally related cytokines, has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis. Recombinant murine IL-17F is a disulfide-linked homodimer of 30 kDa, consisting of two 134 amino acid residue chains.

Sequence

MRKNPKAGVP ALQKAGNCPP LEDNTVRVDI RIFNQNQGIS VPREFQNRSS SPWDYNITRD PHRFPSEIAE AQCRHSGCIN AQGQEDSTMN SVAIQQEILV LRREPQGCSN SFRLEKMLLK VGCTCVKPIV HQAA

性质

recombinant	expressed in E. coli
assay	≥98% (HPLC)
	≥98% (SDS-PAGE)
form	lyophilized
mol wt	mol wt 30 kDa
impurities	<0.1 EU/μg endotoxin, tested
suitability	cell culture tested
UniProt accession no.	Q7TNI7
shipped in	wet ice
storage temp.	?20°C
Gene Information	mouse ... IL17F(257630)