生物来源

human trachea (normal surface epithelium)

质量水平

100

包装

pkg of 500,000 cells

生长模式

Adherent

核型

2n = 46

形态学

epithelial

应用

cell culture | mammalian: suitable

相关疾病

cardiovascular diseases

运输

dry ice

储存温度

−196°C

相关类别

Primary Cells

一般描述

HTEpC provide a useful model system to study all aspects of epithelial function and disease, particularly those related to airway viral infections, as well as tissue repair mechanisms, signaling changes and potential treatments relevant to lung injuries, mechanical and oxidative stress, pulmonary diseases and smoking.

HTEpC have been used in a study investigating the role of goblet cell hyperplasia, possibly mediated by the expression of SPDEF, to the pathogenesis of chronic pulmonary diseases (Park, 2007).

Characterization: the cells have a characteristic morphology consistent with an epithelial origin and are positive for epithelial cell marker cytokeratin 18.

细胞系来源

Trachea

应用

epithelial function, tissue repair, cell signaling, lung injury treatment, mechanical and oxidative stress tests, lung lubrication, humidity maintenance, cleaning of respiratory tract, testing of drugs, toxins and carcinogens, respiratory function

组分

Basal Medium containing 10% FBS & 10% DMSO

制备说明

• 1st passage, >500,000 cells in Basal Medium containing 10% FBS & 10% DMSO

• Can be cultured at least 16 doublings

传代培养常规

Please refer to the HTEpC Culture Protocol.