详细说明
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重要规格表
| Analytes Available | Species Reactivity | Key Applications | Detection Methods |
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| Insulin | H | ELISA | Fluorescent, Colorimetric |
| Description | |
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| Catalogue Number | EZHI-14K |
| Description | Human Insulin ELISA |
| Background Information | Insulin, a 5.8 kDa hormone, is secreted by the islet beta cells in the pancreas. |
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| Product Information | |
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| Detection method | Fluorescent Colorimetric |
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| Applications | |
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| Application | This Human Insulin ELISA is used to measure & quantify insulin levels in Metabolism & Endocrine research. |
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| Application Notes | 2 hour assay, room temperature Sample ≤ 20 μL serum, plasma, or tissue culture medium |
| Biological Information | |
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| Entrez Gene Number |
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| Entrez Gene Summary | After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. |
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| UniProt Number |
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| UniProt Summary | FUNCTION: SwissProt: P01308 # Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. SIZE: 110 amino acids; 11981 Da SUBUNIT: Heterodimer of a B chain and an A chain linked by two disulfide bonds. SUBCELLULAR LOCATION: Secreted. DISEASE:SwissProt: P01308 # Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730]. SIMILARITY: SwissProt: P01308 ## Belongs to the insulin family. |
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| Physicochemical Information | |
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| Linearity of Dilution | 96–112% |
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| Material Size | 96-well strip plate |
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