2089205-64-9
PROTAC RIPK degrader-6(PROTAC RIPK degrader-6)
CAS: 2089205-64-9
化学式: C43H48N6O11S2
中文名 | PROTAC RIPK degrader-6 |
英文名 | PROTAC RIPK degrader-6 |
英文别名 | PROTAC RIPK degrader-6 Acetamide, 2-[2-[2-[2-[2-[[4-(5-benzothiazolylamino)-6-[(1,1-dimethylethyl)sulfonyl]-7-quinolinyl]oxy]ethoxy]ethoxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-4-yl]- |
CAS | 2089205-64-9 |
化学式 | C43H48N6O11S2 |
分子量 | 889 |
密度 | 1.398±0.06 g/cm3(Predicted) |
沸点 | 1111.1±65.0 °C(Predicted) |
酸度系数 | 10.68±0.40(Predicted) |
存储条件 | -20°C |
体外研究 | PROTACs is useful for the targeted degradation of proteins and other polypeptides which on the one end binds to the cereblon and on the other end to the target protein (RIP2 kinase). By bringing the target protein in close proximity to the E3-Ligase, these compounds form a ternary complex leading to polyubiquitination of the target protein inducing its degradation. |