磺胺吡啶,英文名:Sulfapyridine,CAS:144-83-2,化学式:C11H11N3O2S,分子量:249.29,密度:1.3220 (rough estimate),熔点:191-193

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144-83-2 询问

磺胺吡啶(Sulfapyridine)

CAS: 144-83-2

化学式: C11H11N3O2S

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中文名	磺胺吡啶
英文名	Sulfapyridine
别名	磺胺吡啶 2-磺胺吡啶 磺胺吡啶熔点标准物 柳氮磺胺吡啶EP杂质J 柳氮磺吡啶杂质J (EP) 对胺-N-2-吡啶苯磺醯胺 對胺-N-2-吡啶苯磺醯胺 柳氮磺胺吡啶杂质J (EP) 4-氨基-N-(2-吡啶基)苯磺酰胺
英文别名	THAP11 CTG-B43a CTG-B45d HRIHFB2206 Sulfapyridine Sulfapyridine (Dagenan) Sulfapyridine Solution, 100ppm Monoclonal Anti-THAP11 antibody produced in mouse 2-(4-Aminobenzenesulfonamido)pyridineN'-2-Pyridylsulfanilide2-Sulfanilamidopyridine
CAS	144-83-2
EINECS	205-642-7
化学式	C11H11N3O2S
分子量	249.29
InChI	InChI=1/C11H11N3O2S/c12-9-4-6-10(7-5-9)17(15,16)14-11-3-1-2-8-13-11/h1-8H,12H2,(H,13,14)
密度	1.3220 (rough estimate)
熔点	191-193°C
沸点	473.5±51.0 °C(Predicted)
闪点	240.2°C
蒸汽压	3.9E-09mmHg at 25°C
溶解度	DMSO (微溶) 、甲醇 (微溶)
折射率	1.6740 (estimate)
酸度系数	pKa 8.48(H2Ot = 25I = 0.05) (Uncertain)
存储条件	Keep in dark place,Sealed in dry,Room Temperature
稳定性	稳定。可燃。保护光线。与强氧化剂不相容。
外观	整洁
颜色	White to Off-White
Merck	14,8938
BRN	222065
物化性质	黄棕至白色粉末。熔点191-193℃。微溶于水。
MDL号	MFCD00038036
体外研究	Sulfapyridine inhibits production of IL-8, chemokine (C-X-C motif) ligand 1 (CXCL1), and monocyte chemotactic protein-1 (MCP-1) in synovial cells of rheumatoid arthritis (RA). MIC range of Sulfapyridine for Y. enterocolitica is 3.1-25 μg/mL and for Salmonella 25-100 μg/mL. Campylobacter jejuni/coli are less susceptible to Sulfapyridine with MIC values ranging from 200 to 800 μg/mL. Shigella and three of five E. coli strains are resistant to 1600 μg/mL of sulfapyridine. Two strains of E. coli are inhibited by 25 μg/mL.
体内研究	Sulfapyridine (1 and 10 μg/kg; i.p.) significantly inhibits systemic allergic reaction induced by compound 48/80 in rats.
危险品标志	Xi - 刺激性物品
风险术语	36/37/38 - 刺激眼睛、呼吸系统和皮肤。
安全术语	S22 - 切勿吸入粉尘。 S24/25 - 避免与皮肤和眼睛接触。 S36 - 穿戴适当的防护服。 S26 - 不慎与眼睛接触后，请立即用大量清水冲洗并征求医生意见。
WGK Germany	2
RTECS	DA9625000
海关编号	29350010
Hazard Class	IRRITANT
上游原料	4-氯-N-(吡啶-2-基)苯磺酰胺 N-(4-(N-(吡啶-2-基)氨磺酰)苯基)乙酰胺
下游产品	柳氮磺吡啶
参考资料 展开查看	1. [IF=7.46] Zijun Xu et al."Machine learning assisted dual-emission fluorescence/colorimetric sensor array detection of multiple antibiotics under stepwise prediction strategy."Sensor Actuat B-Chem. 2022 May;359:131590