右磷丝氨酸,英文名:O-phospho-L-serine,CAS:407-41-0,化学式:C3H8NO6P,分子量:185.07,密度:1.809±0.06 g/cm3(Predicted),熔点:_信息_文库

右磷丝氨酸,英文名:O-phospho-L-serine,CAS:407-41-0,化学式:C3H8NO6P,分子量:185.07,密度:1.809±0.06 g/cm3(Predicted),熔点:

2024-10-31 0

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407-41-0

右磷丝氨酸(O-phospho-L-serine)

CAS: 407-41-0

化学式: C3H8NO6P

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中文名	右磷丝氨酸
英文名	O-phospho-L-serine
别名	右磷丝氨酸磷酸化丝氨酸 L-丝氨酸O-磷酸 L-O-磷酸丝氨酸 L-丝氨酸O-型磷酸 O-磷酸-L-丝氨酸 L-2-氨基-3-羟基丙酸三磷酸 L-2-氨基-3-羟基丙酸3-磷酸
英文别名	dexfosfoserine L-PHOSPHOSERINE H-Ser(PO3H2)-OH H-SER(PO3H2)-OH Phospho-L-serine L-O-PHOSPHOSERINE O-Phosho-L-serine L-O-Phosphoserine O-phospho-L-serine L-Serine phosphate O-Phosphorylserine O-phosphono-L-serine L-SERINE-O-PHOSPHATE Phosphoserinebariumsalt MDI Polyols for PU Foams L-Phosphoserine Anhydrous DL-O-Phosphoserine barium salt PHOSPHATIDYLETHANOLAMINE(EGG)(RG) L-(+)-serine 3-(dihydrogen phosphate) (2S)-2-ammonio-3-(phosphonatooxy)propanoate
CAS	407-41-0
EINECS	206-986-0
化学式	C3H8NO6P
分子量	185.07
InChI	InChI=1/C3H8NO6P/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/p-2/t2-/m0/s1
InChIKey	BZQFBWGGLXLEPQ-UWTATZPHSA-N
密度	1.809±0.06 g/cm3(Predicted)
熔点	190°C(lit.)
沸点	475.4±55.0 °C(Predicted)
比旋光度	[α]D20 +14～+18°(c=5,dil.HCl)
闪点	241.3°C
水溶性	28.34g/L at 20℃
蒸汽压	0Pa at 20℃
溶解度	H2O: 50mg/ml热，透明，无色至微黄色
酸度系数	pK1:2.08;pK2:5.65;pK3:9.74 (25°C)
存储条件	under inert gas
外观	结晶性粉末
颜色	White
Merck	14,7363
BRN	1726826
MDL号	MFCD00065935
体外研究	O-Phospho-L-serine (l-SOP) weakly binds to mGluR1, and antagonizes the effects of l-glutamate. l-SOP activates the group III receptors (mGluR4, mGluR6, mGluR7, and mGluR8), but mGluR7 has much lower affinity for l-SOP than the other group III receptors and also displays lower efficacy for both ligands. O-Phospho-L-serine (l-SOP) generates enhanced intracellular calcium responses in mGluR4 transfected cells. l-SOP inhibits the l-glutamate mediated mGluR1 response, with a K i of 1 mM; l-SOP displays a substantially more potent inhibition of mGluR2 activation, with a K i of 1 μM, three orders-of-magnitude more potent than for mGluR1. l-SOP induces membrane potential changes in HEK/TRPC4 cells transfected with mGluR4 or mGluR6. l-SOP induces TRPC4β activation mediated by Gα i/o proteins. O-Phospho-L-serine (L-SOP) inhibits Müller glia proliferation, without affecting light-induced photoreceptor cell death. L-SOP disrupts Müller glia proliferation subsequent to or in parallel with the activation of ascl1a and stat3 expression in the light-damaged retina. L-SOP inhibits cone cell regeneration in the light-damaged retina.
危险品标志	Xn - 有害物品
风险术语	21/22 - 皮肤接触及吞食有害。
安全术语	36/37 - 穿戴适当的防护服和手套。
危险品运输编号	UN 3261 8 / PGII
WGK Germany	3
FLUKA BRAND F CODES	10
海关编号	29225090
下游产品	S-2-羟乙基-L-半胱氨酸

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